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Surgery / General Surgery - Endocrine & Oncologic

Rebecca L. Aft, MD, PhD

Current Position
Associate Professor, Surgery
Division of General Surgery
Cancer and Endocrine Surgery Section


Specialty Areas
Endocrine/Cancer Surgery
Breast Surgery
Oncologic Surgery
Breast Oncology
Breast Health

Patients Seen At
Center for Advanced Medicine
Joanne Knight Breast Health Center
4921 Parkview Place, F, 5
St. Louis, MO  63110
314-362-2280
Fax:   314-454-5509
View Floor Map  View Campus Map   View Driving Directions

Mailing Address
Washington University School of Medicine
Department of Surgery
660 S. Euclid Avenue, Campus Box 8109
St. Louis, MO  63110

Areas of Clinical Interest
breast disease, breast cancer, oncology, general surgery,

Areas of Research Interest
breast disease, breast cancer, oncology

Board Certification
General Surgery -- Certified

Medical Education
B.S.: University of Wisconsin, Madison, Wisconsin, 1978
Ph.D.: University of Wisconsin, Madison, Wisconsin, 1983
Medical Degree: Washington University School of Medicine, St. Louis, MO, 1992
Hospital Affiliations
Barnes-Jewish Hospital
Barnes-Jewish West County Hospital
John Cochran Veterans Hospital

Major or Recent Publications/Awards

Awards

Listed in Best Doctors in America, 2008, 2010 (Best Doctors, Inc)

Books and Book Chapters

Veeramachanei N, Aft R. Principles of Surgical Oncology. In: Govindan R (ed.). Cancer: Principles and Practice of Oncology Review. 2005.

Cohen M, Aft R, Eberlein T. Breast Surgery. In: Washington Manual of Surgery, eds. Doherty G, et al. 2002

Aft R. Principles of Surgical Oncology. In: Washington Manual of Oncology, eds., Govindan R and Arquette M. 2002

Yim J, Aft RL, and Eberlein T. Breast Disease. Doherty G, et al. Eds. In: Washington Manual of Surgery. Boston: Little, Brown and Company, 1998

Aft RL, Bolling W. Trauma.Baumann D, Creswell L, Doherty G, Goss J, Lairmore T. eds., In: The Washington Manual of Surgery. Boston: Little, Brown and Company, 1995

Selected Journal Articles

Schootman M, Jeffe DB, Gillanders WE, Yan Y, Aft R. The effects of radiotherapy for the treatment of contralateral breast cancer. Breast Cancer Research and Treatment. 2006 Oct 11; [Epub ahead of print]

Schootman M, Fuortes L, Aft R. Prognosis of metachronous contralateral breast cancer according to stage at diagnosis: The importance of early detection. Breast Cancer Research and Treatment. 2006;99(1):91-95. Epub 2006 Mar 23.

Schootman M, Jeffe D, West M, Aft R. Self-report by elderly patients of breast cancer treatment were acceptable alternatives to Surveillance, Epidemiology, and End Results (SEER) abstract data. Journal of Clinical Epidemiology. 2005;58:1316-1319.

Perrone J, Soper N, Eagon J, Klingensmtih M, Aft R, Frisella M, Brunt L. Perioperative outcomes and complications of laparoscopic ventral hernia repair. Surgery. 2005;138: 708-715.

Schootman M, Jeffe D, Reschke A, Aft R. The full potential of breast cancer screening has not yet been realized in the United States. Breast Cancer Research and Treatment. 2004;85:219-222.

Aft R, Lewis J, Zhang F, Welch M. Enhancing targeted radiotherapy by 64Cu-ATSM using 2-deoxy-2-glucose. Cancer Research. 2003;63:5496-5504.

Schootman M, Jeffe D, Reschke A, Aft R. Disparities in breast cancer screening: Important temporal observations among those of lower socioeconomic status and with reduced access to medical care. Cancer Epidemiology and Biomarkers. 2003;14:419-425.

Lin X, Zhang F, Bradbury C, Kaushal A, Li L, Spitz D, Aft R, Gius D. 2-deoxy-d-glucose induced cytotoxic and radiosensitization in tumor cells is mediated via disruptions in thiol metabolism. Cancer Research. 2003;63:3413-3417.

Aft RL, Zhang R, Gius D. Cheomsensitizing and cytotoxic effects of 2-deoxy-d-glucose on breast cancer cells. In Preparation, 2002

Schootman M, Jeffe D, Reschke A, Aft R. The full potential of breast cancer screening has not yet been realized in the United States. Cancer, Submitted, 2002

Jeffe D, Schootman M, Reschke A, Aft R. African American users of hormone replacment therapy present with larger breast cancers. Cancer, Submitted, 2002

Aft RL, Zhang FW, Gius D. Evaluation of 2-deoxy-D-glucose as a chemotherapeutic agent: Mechanism of cell death. Br J Cancer 2002; Sep 23;87(7):805-12

Schootman M, Aft R. Rural-urban differences in radiation therapy for ductal carcinoma in-situ of the breast. Breast Cancer Res Treat 2001; Jul;68(2):117-25

Schmieg RE Jr, Tinsley KW, Swanson PE, Karl IE, Aft R, Buchman TG, Hotchkiss RS. Rapid onset of hepatocyte apoptosis in a patient with trauma. J Trauma 2000; Sep;49(3):542-6

Perez C, Taylor M, Aft R, Doherty D, Levy J, Young G. Ductal carcinoma in situ: Management of breast relapses after initial treatment. Sem Br Dis 2000; 3:239-247

Zhang F, Aft R. Inhibition of growth in breast cancer cell lines by interference with carbohydrate metabolism. Proc Amer Assoc Cancer Research 1999

Aft RL, Mueller GC. Covalent cross linking and degradation of glutathoine reductase by hemin. Life Sciences 1985; 36:2153-2161

Aft RL, Mueller GC. Hemin mediated DNA strands scission. J Bio Chem 1984; 258:301-304

Aft RL, Mueller GC, Hemin mediated oxidative degradation of proteins. J Bio Chem 1983; 259:301-304


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For more articles and abstracts, take this off-site link to the National Library of Medicine Pub Med page for Dr Aft.

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Copyright 2010 Washington University School of Medicine