Rebecca L. Aft, MD, PhD
Current Position
Associate Professor, Surgery
Division of General Surgery
Cancer and Endocrine Surgery Section
Specialty Areas
Endocrine/Cancer Surgery
Breast Surgery
Oncologic Surgery
Breast Oncology
Breast Health
Mailing Address
|
Washington University School of Medicine Department of Surgery
660 S. Euclid Avenue, Campus Box 8109
St. Louis,
MO
63110
|
Areas of Clinical Interest
breast disease, breast cancer, oncology, general surgery,
Areas of Research Interest
breast disease, breast cancer, oncology
Board Certification
General Surgery
--
Certified
Medical Education
B.S.: University of Wisconsin, Madison, Wisconsin, 1978
Ph.D.: University of Wisconsin, Madison, Wisconsin, 1983
Medical Degree: Washington University School of Medicine, St. Louis, MO, 1992
Hospital Affiliations
Barnes-Jewish Hospital
Barnes-Jewish West County Hospital
John Cochran Veterans Hospital
Major or Recent Publications/Awards
Awards
Listed in Best Doctors in America, 2008, 2010 (Best Doctors, Inc)
Books and Book Chapters
Veeramachanei N, Aft R. Principles of Surgical Oncology. In:
Govindan R (ed.). Cancer: Principles and Practice of Oncology Review.
2005.
Cohen M, Aft R, Eberlein T. Breast Surgery. In: Washington Manual of Surgery, eds. Doherty G, et al. 2002
Aft R. Principles of Surgical Oncology. In: Washington Manual of Oncology, eds., Govindan R and Arquette M. 2002
Yim J, Aft RL, and Eberlein T. Breast Disease. Doherty G, et al. Eds.
In: Washington Manual of Surgery. Boston: Little, Brown and Company,
1998
Aft RL, Bolling W. Trauma.Baumann D, Creswell L, Doherty G, Goss J,
Lairmore T. eds., In: The Washington Manual of Surgery. Boston: Little,
Brown and Company, 1995
Selected Journal Articles
Schootman M, Jeffe DB, Gillanders WE, Yan Y, Aft R. The effects of
radiotherapy for the treatment of contralateral breast cancer. Breast
Cancer Research and Treatment. 2006 Oct 11; [Epub ahead of print]
Schootman M, Fuortes L, Aft R. Prognosis of metachronous contralateral
breast cancer according to stage at diagnosis: The importance of early
detection. Breast Cancer Research and Treatment. 2006;99(1):91-95. Epub
2006 Mar 23.
Schootman M, Jeffe D, West M, Aft R. Self-report by elderly patients of
breast cancer treatment were acceptable alternatives to Surveillance,
Epidemiology, and End Results (SEER) abstract data. Journal of Clinical
Epidemiology. 2005;58:1316-1319.
Perrone J, Soper N, Eagon J, Klingensmtih M, Aft R, Frisella M, Brunt
L. Perioperative outcomes and complications of laparoscopic ventral
hernia repair. Surgery. 2005;138: 708-715.
Schootman M, Jeffe D, Reschke A, Aft R. The full potential of breast
cancer screening has not yet been realized in the United States. Breast
Cancer Research and Treatment. 2004;85:219-222.
Aft R, Lewis J, Zhang F, Welch M. Enhancing targeted radiotherapy by
64Cu-ATSM using 2-deoxy-2-glucose. Cancer Research. 2003;63:5496-5504.
Schootman M, Jeffe D, Reschke A, Aft R. Disparities in breast cancer
screening: Important temporal observations among those of lower
socioeconomic status and with reduced access to medical care. Cancer
Epidemiology and Biomarkers. 2003;14:419-425.
Lin X, Zhang F, Bradbury C, Kaushal A, Li L, Spitz D, Aft R, Gius D.
2-deoxy-d-glucose induced cytotoxic and radiosensitization in tumor
cells is mediated via disruptions in thiol metabolism. Cancer Research.
2003;63:3413-3417.
Aft RL, Zhang R, Gius D. Cheomsensitizing and cytotoxic effects of
2-deoxy-d-glucose on breast cancer cells. In Preparation, 2002
Schootman M, Jeffe D, Reschke A, Aft R. The full potential of breast
cancer screening has not yet been realized in the United States.
Cancer, Submitted, 2002
Jeffe D, Schootman M, Reschke A, Aft R. African American users of
hormone replacment therapy present with larger breast cancers. Cancer,
Submitted, 2002
Aft RL, Zhang FW, Gius D. Evaluation of 2-deoxy-D-glucose as a
chemotherapeutic agent: Mechanism of cell death. Br J Cancer 2002; Sep
23;87(7):805-12
Schootman M, Aft R. Rural-urban differences in radiation therapy for
ductal carcinoma in-situ of the breast. Breast Cancer Res Treat 2001;
Jul;68(2):117-25
Schmieg RE Jr, Tinsley KW, Swanson PE, Karl IE, Aft R, Buchman TG,
Hotchkiss RS. Rapid onset of hepatocyte apoptosis in a patient with
trauma. J Trauma 2000; Sep;49(3):542-6
Perez C, Taylor M, Aft R, Doherty D, Levy J, Young G. Ductal carcinoma
in situ: Management of breast relapses after initial treatment. Sem Br
Dis 2000; 3:239-247
Zhang F, Aft R. Inhibition of growth in breast cancer cell lines by
interference with carbohydrate metabolism. Proc Amer Assoc Cancer
Research 1999
Aft RL, Mueller GC. Covalent cross linking and degradation of glutathoine reductase by hemin. Life Sciences 1985; 36:2153-2161
Aft RL, Mueller GC. Hemin mediated DNA strands scission. J Bio Chem 1984; 258:301-304
Aft RL, Mueller GC, Hemin mediated oxidative degradation of proteins. J Bio Chem 1983; 259:301-304
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For more articles and abstracts, take this off-site link to the National Library of Medicine Pub Med page for Dr Aft.